Ninety years ago, Gabriella di Luca promised to protect the family of her dying lover. She failed to keep that promise. She was too far away to stop the devil that murdered the eldest Van Helsing son. Years later, Gabby learns the devil has resurfaced. She arrives in Hampton, TX, determined to stop the devil before it can lay a bloody hand on the remaining three brothers.
However, madness is spreading through Hampton. She suspects the devil is using this madness to test a drug which has a side effect of demonic possession. Gabby rushes to end the source of the madness only to fall victim to it. For a woman cursed with eternal life, dying is no threat. However, Gabby must stop the devil’s plot or risk losing her most precious possession: her mind.